D-Galactose-induced accelerated aging model: an overview.

D-Galactose-induced accelerated aging model: an overview.
Biogerontology. 2019 Sep 20;:
Authors: Azman KF, Zakaria R
Abstract
To facilitate the process of aging healthily and prevent age-related health problems, efforts to properly understand aging mechanisms and develop effective and affordable anti-aging interventions are deemed necessary. Systemic administration of D-galactose has been established to artificially induce senescence in vitro and in vivo as well as for anti-aging therapeutic interventions studies. The aim of this article is to comprehensively discuss the use of D-galactose to generate a model of accelerated aging and its possible underlying mechanisms involved in different tissues/organs.
PMID: 31538262 [PubMed - as supplied by publisher]

Source: Biogerontology - September 19, 2019 Category: Geriatrics Authors: Azman KF, Zakaria R Tags: Biogerontology Source Type: research