Structural Characterisation of Amorphous Solid Dispersions via Metropolis Matrix Factorisation of Pair Distribution Function Data

Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC06753A, CommunicationHarry Geddes, Helen Blade, Leslie Peter Hughes, James Francis McCabe, Andrew Goodwin We measure the X-ray pair distribution functions (PDFs) of a series of felodipine:copovidone amorphous solid dispersions. Using a newly-developed Metropolis Matrix Factorisation (MMF) algorithm we extract from these data the... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chem. Commun. latest articles - September 21, 2019 Category: Chemistry Authors: Harry Geddes Source Type: research