Internet-based cognitive behavioral therapy aimed at alleviating treatment-induced menopausal symptoms in breast cancer survivors: moderators and mediators of treatment effects

Many young breast cancer (BC) survivors are confronted with menopausal symptoms caused by their BC treatment [1]. The most prevalent and disruptive menopausal symptoms are hot flushes and night sweats (HF/NS) which negatively affect health-related quality of life (HRQOL), and can result in women discontinuing their endocrine treatment [2 –5]. A cognitive behavioral therapy (CBT) program was developed by Hunter and colleagues to help women cope with these HF/NS [6,7]. Four randomized controlled trials (RCTs) have provided evidence of the efficacy of this program, delivered in groups or in self-help or guided self-help format, in re ducing the perceived impact of HF/NS in healthy women (MENOS 2 trial, MENOS@work trial) [8,9] and in BC survivors (MENOS 1 trial and EVA trial) [10,11].

Source: Maturitas - September 17, 2019 Category: Primary Care Authors: Vera Atema, Marieke van Leeuwen, Jacobien M. Kieffer, Hester S.A. Oldenburg, Marc van Beurden, Myra S. Hunter, Neil K. Aaronson Source Type: research