Circulating placental growth factor (PLGF) concentration in pregnant women with endometriosis: a case-control study

It is widely accepted that angiogenesis is pivotal to the establishment of endometriotic lesions and it is fundamental in the regulation of placental development starting from the early stages of pregnancy. Circulating vascular endothelial growth factor and placental growth factor (PLGF) levels have been reported to be increased in women with endometriosis when compared with controls, conversely decreased levels of PLFG have been reported in pregnant women developing preeclampsia. For this reason, the presence of endometriosis might be a protective factor for the development of early onset preeclampsia during pregnancy, since the increased level of PLGF in these patients might promote placental development.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research