Obesity Poses Much Bigger Risk for Diabetes Than Bad Genes Obesity Poses Much Bigger Risk for Diabetes Than Bad Genes
The study highlights the dominance of obesity as a risk factor for type 2 diabetes and reinforces the"importance of weight management in diabetes prevention...in all genetic risk groups," say researchers.Medscape Medical News
The evidence is clear. Bariatric surgery provides wide-ranging benefits to adolescents with obesity and type 2 diabetes, says Dr Louise Baur.Medscape Diabetes &Endocrinology
Conditions: Obesity; Diabetes Mellitus, Type 2; Insulin Resistance Intervention: Other: Methylation status Sponsor: University of Arizona Recruiting
Condition: Childhood Obesity Intervention: Behavioral: Evaluation of whiteboard videos Sponsors: The Hospital for Sick Children; University of Ottawa Not yet recruiting
The Metabolic Syndrome may be tentatively defined as the clustering of several metabolic risk factors in the same individual. A progressively higher number of children and adolescents is affected by this syndrome worldwide, mainly as a consequence of the constant increase of the prevalence of obesity and sedentary habits. As obesity, the chance that the metabolic syndrome traks into adulthood is high. Moreover, the evidence of an association between the duration of the exposition to metabolic risk factors and morbidity and mortality justifies early treatment and prevention of the metabolic syndrome in both children and ado...
ConclusionStudies on arthroplasty survival should systematically mention gender and diabetes status and beware of potential group incomparability.Level of evidenceIII, cohort study.
ConclusionUrinalysis screening followed by evaluation of risk factors is a simple and efficient way to identify children with diabetes in schools.
FRIDAY, Oct. 11, 2019 -- Poor glycemic control is associated with increased risks for stroke and death among patients with type 2 diabetes, according to a study published online Oct. 1 in Diabetes, Obesity and Metabolism. Alexander Zabala, M.D.,...
Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a remedy for various conditions with pathogenesis shared by metabolic diseases. Reported here is our characterization of its therapeutic profiles in three mouse models with distinctive pathological features of metabolic syndrome (MetS). Our results firstly showed that AF alleviated high fat (HF) induced obesity and associated glucose intolerance, suggesting its therapeutic efficacy for MetS. In the type 2 diabetes (T2D) model induced by a combination of HF and low doses of streptozotocin, AF lowered hyperglycaemia and improved insuli...
ConclusionThese results indicate that enhanced brain insulin signaling transduction and brain glucose utilization play important roles in the antidiabetic effect of DJB.