GCT-P05 - Metastatic burned-out germ cell tumour of the testes and growing teratoma syndrome in a paediatric patient

Publication date: 2019Source: European Urology Supplements, Volume 18, Issue 4Author(s): P. Mahajan, S. Gruner, J.G. Nuchtern, G. Godoy, R. Venkatramani
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research

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ConclusionRobot-assisted laparoscopy did not reduce intraoperative spillage of dermoid cyst contents compared to traditional laparoscopy or laparotomy. In patients with large (>6cm) dermoid cysts the use of RAL decreased blood loss, length of postoperative hospital stay, need for inpatient admission and conversion to LAP (compared to SLA), but increased the length of surgery and hospital cost compared to LAP. We conclude that larger dermoid cysts may be treated with RAL instead of LAP. Smaller cysts may have equivalent outcomes with traditional laparoscopic techniques.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
RESUMO Objetivo: Revisar as evid ências científicas que reportem o período de início da nutrição enteral na população pediátrica vítima de queimadura e seus achados. Métodos: Revisão sistemática e metanálise de estudos clínicos randomizados comparando nutrição enteral precoce e nutrição enteral tardia em indiví duos de 1 mês de idade a 18 anos com queimaduras. As bases de dados MEDLINE/PubMed, Embase e Cochrane Library foram acessadas utilizando os termos "burns", "...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
The objective of this literature review is to present the theoretical and practical aspects of extracorporeal membrane oxygenation support for respiratory and/or cardiac functions in critically ill patients.
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Well recognized is the variety of presentations of endometriosis lesions beyond simply the classic "black powder-burn lesions" of John Sampson (1927). No standardized nomenclature exists to provide either gross morphologic description nor classification of the variety of endometriosis lesions. Borrowing from Dermatology systems of descriptive nomenclature, this video reviews a classification system specific for endometriosis focusing on Primary as well as Secondary lesion characteristics and then demonstrates use of the classification system for a variety of different endometriosis lesions.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Virtual Poster Session 3: Endometriosis (10:20 AM – 10:30 AM) 10:20 AM: STATION O Source Type: research
In conclusion, there are many anti-aging strategies in development, some of which have shown considerable promise for slowing down aging or delaying the onset of age-related diseases. From multiple pre-clinical studies, it appears that upregulation of autophagy through autophagy enhancers, elimination of senescent cells using senolytics, transfusion of plasma from young blood, neurogenesis and BDNF enhancement through specific drugs are promising approaches to sustain normal health during aging and also to postpone age-related diseases. However, these approaches will require critical assessment in clinical trials to determ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract Patient specific induced pluripotent stem cells (iPSCs) have been recognized as a possible source of cells for skin tissue engineering. They have the potential to greatly benefit patients with large areas of burned skin or skin defects. However, the integration virus-based reprogramming method is associated with a high risk of genetic mutation and mouse embryonic fibroblast feeder-cells may be a pollutant. In the present study, human skin fibroblasts (HSFs) were successfully harvested from patients with burns and patient-specific iPSCs were generated using a non-integration method with a feeder-...
Source: International Journal of Molecular Medicine - Category: Molecular Biology Authors: Tags: Int J Mol Med Source Type: research
We report a case of a 19-year-old man presenting to our institute with a right testicular lesion, evidence of mediastinal and abdominal lymph node metastasis, and high levels of GCT serum biomarkers. After orchiectomy, the histopathological examination showed a mixed GCT: mature teratoma, immature teratoma, and histological features of testicular cancer regression (burned-out phenomenon). The patient underwent first-line chemotherapy (BEP regimen) which resulted in a complete instrumental and biochemical response after 4 cycles. Teratoma is considered a less aggressive type of GCT. In this particular case, metastatic disea...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
We report a case of a 19-year-old man presenting to our institute with a right testicular lesion, evidence of mediastinal and abdominal lymph node metastasis, and high levels of GCT serum biomarkers. After orchiectomy, the histopathological examination showed a mixed GCT: mature teratoma, immature teratoma, and histological features of testicular cancer regression (burned-out phenomenon). The patient underwent first-line chemotherapy (BEP regimen) which resulted in a complete instrumental and biochemical response after 4 cycles. Teratoma is considered a less aggressive type of GCT. In this particular case, metastatic disea...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
By MARTIN A. SAMUELS I posted an essay on The Health Care Blog entitled The Prevention of Physician Burnout: A Nine Step Program. Here is an example of how this works. Recall the wonderful children’s book by Leo Lionni, Frederick. Let me remind you of it. A family of mice begins to store away food and supplies for the long winter ahead.  Most are practical and gather corn, grains, and straw. One of the mice, Frederick, instead collects rays of sun, colors of the rainbow, and words to remember.  When winter arrives the family begins to use up their practical supplies.  They become irritable and angry a...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Burnout Frederick Martin Samuels Source Type: blogs
By MARTIN A. SAMUELS I posted an essay on The Health Care Blog (entitled The Prevention of Physician Burnout: A Nine Step Program. Here is an example of how this works. Recall the wonderful children’s book by Leo Lionni, Frederick. Let me remind you of it. A family of mice begins to store away food and supplies for the long winter ahead.  Most are practical and gather corn, grains, and straw. One of the mice, Frederick, instead collects rays of sun, colors of the rainbow, and words to remember.  When winter arrives the family begins to use up their practical supplies.  They become irritable and angry ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
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