MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES)

Our aim was to introduce a simplified MRI instrument, Rapid OsteoArthritis MRI Eligibility Score (ROAMES), for defining structural eligibility of patients for inclusion in disease-modifying osteoarthritis drug trials using a tri-compartmental anatomic approach that enables stratification of knees into different structural phenotypes and includes diagnoses of exclusion. We also aimed to define overlap between phenotypes and determine reliability.

Source: Osteoarthritis and Cartilage - September 8, 2019 Category: Rheumatology Authors: Frank W. Roemer, Jamie Collins, C. Kent Kwoh, Michael J. Hannon, Tuhina Neogi, David T. Felson, David J. Hunter, John A. Lynch, Ali Guermazi Source Type: research