419 Demodex Mites and Rosacea: Modulation of Inflammation in Skin Resident Cells

Demodex mites are normal residents of the pilosebaceous follicles of healthy human facial skin, at low density, without inducing inflammatory response by skin resident cells (SRCs). When the Demodex population increases, such as in rosacea, an inflammatory response is initiated. The aim of this study is to evaluate how Demodex mites modulate inflammation in SRCs. Skin biopsies from rosacea patients were assessed histologically. Hair follicles were dilated or ruptured, contained mites and occasional inflammatory cells.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Innate Immunity and Inflammation Source Type: research