Prognostic factors of interstitial lung disease progression at sequential HRCT in anti-synthetase syndrome

ConclusionsAt the onset of ASS, some clinical features and HRCT pattern of ILD may suggest an unfavorable outcome of lung involvement on HRCT, even with routine therapy. These factors may contribute to the high long-term mortality of ASS.Key Points• Evaluation of lung involvement on HRCT is important in the follow-up of patients with interstitial lung disease related to anti-synthetase syndrome (ASS-ILD).• The interstitial lung disease related to ASS responds to the treatment variably.• Some clinical and imaging characteristics are associated with poor prognosis in patients with ASS-ILD, including fever at diagnosis, a lower serum CD3+/CD4+level, and a UIP pattern.
Source: European Radiology - Category: Radiology Source Type: research