In-vitro activity of active ingredients of disinfectants against drug-resistant fungi

Publication date: Available online 27 July 2019Source: Journal of Hospital InfectionAuthor(s): R. Stauf, D. Todt, E. Steinmann, P-M. Rath, H. Gabriel, J. Steinmann, F.H.H. BrillSummaryThe biocidal activities of peracetic acid and ethanol were tested against nine clinical fungal isolates and four reference strains. Ethanol was active (≥4.0 log10 reduction) against yeasts at a concentration of 50% v/v and against moulds at 80% v/v. Exposure times in both cases were 1 min. Peracetic acid was active as a 0.25% solution against yeasts and as a 0.5% solution against moulds; exposure times in both cases were 5 min. Compared with the reference strains, clinical isolates, including multi-drug-resistant strains, showed similar or higher sensitivity to the active ingredients of disinfectants in vitro.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research