Effects of red ginseng on the elastic properties of human skin

Publication date: Available online 21 August 2019Source: Journal of Ginseng ResearchAuthor(s): Moon Young Park, Se Jik Han, Donggerami Moon, Sangwoo Kwon, Jin-Woo Lee, Kyung Sook KimAbstractBackgroundRed ginseng contains components that can be used in skincare to delay the aging process, including microelements, vitamins, essential oils, and fatty acids. We investigated the effects of red ginseng treatment on skin elasticity by assessing cellular stiffness and measuring collagen protein synthesis.MethodsHuman dermal fibroblasts were treated with red ginseng, and the resulting changes in stiffness were investigated using atomic force microscopy (AFM). Cytoskeletal changes and the mRNA expression of biomarkers of aging, including procollagens I and VII, elastin, and fibrillin-1, were investigated. Collagen in a human skin equivalent treated with red ginseng was visualized via hematoxylin and eosin staining, scanning electron microscopy, and AFM.Results and conclusionThe stiffness of fibroblasts was significantly reduced by treatment with red ginseng concentrations of ≥ 0.8 mg/mL. The F-actin to G-actin ratio decreased after treatment, which corresponded with a change in fibroblast stiffness. The storage modulus (G′) and loss modulus (G″) of skin equivalent were both lowered by red ginseng treatment. This result indicates that the viscoelasticity of skin equivalent can be restored by red ginseng treatment.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research

Related Links:

Publication date: January 2020Source: Materials Science and Engineering: C, Volume 106Author(s): Tahmineh Ahmadi, Ahmad Monshi, Vajihsadat Mortazavi, Mohammad Hossein Fathi, Shahriar Sharifi, Mahshid Kharaziha, Leila Khazdooz, Amin Zarei, Majid Taghian DehaghaniAbstractThe aim of this study was to fabricate and characterize biodegradable polycaprolactone fumarate(PCLF)/gelatin-based nanocomposite incorporated with the 0, 5 and 10 wt% silicon and magnesium co-doped fluorapatite nanoparticles (Si-Mg-FA) membranes using electrospinning process for guided bone regeneration (GBR) and guided tissue regeneration (GTR) applicati...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In this study, we developed a programmed electrospun 3D NF collector. It can precisely control the moving speed of NF collector during electrospinning; thereby fabricating 3D NFs with desired microstructures (pore size, pore volume, and interconnectivity). Four types of polycaprolactone (PCL) 3D NF matrices with different microstructures can be obtained concurrently on the NF collector surface, which are set by different forward moving speed of the NF collector device: NF-zero (no move, as control), NF-low (0.085 mm/min), NF-mid (0.158 mm/min) and NF-high (0.232 mm/min). A linear increase of the NF sheet thickness (f...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: January 2020Source: Materials Science and Engineering: C, Volume 106Author(s): Gholamreza Bahrami, Hosna Ehzari, Shokouh Mirzabeigy, Bahar Mohammadi, Elham ArkanAbstractA sensitive electrochemical sensor for detection of morphine (MPH) at the surface of electrode modified with electrospun magnetic nanofibers (MNFs) was prepared. The features of constructed sensor were evaluated by scanning electron microscopy (SEM), X ray diffraction (XRD) and electrochemical impedance spectroscopy (EIS). The modified sensor was used for MPH analysis using of cyclic voltammetry (CV) and differential pulse voltammetry (DPV...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Authors: Ozaki T, Kinoshita M, Arita H, Kagawa N, Fujimoto Y, Kanemura Y, Sakai M, Watanabe Y, Nakanishi K, Shimosegawa E, Hatazawa J, Kishima H Abstract Brain Tumor Image Analysis (BraTumIA) is a fully automated segmentation tool dedicated to detecting brain tumors imaged by magnetic resonance imaging (MRI). BraTumIA has recently been applied to several clinical investigations; however, the validity of this novel method has not yet been fully examined. The present study was conducted to validate the quality of tumor segmentation with BraTumIA in comparison with results from 11C-methionine positron emission tomogra...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Publication date: Available online 14 September 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Urooj Javed, Asma Ansari, Afsheen Aman, Shah Ali Ul QaderAbstractIndustrial enzymes particularly xylanase have more demand due to its vast commercial application in paper and pulp, food, animal feed industries as well as for bioconversion of lignocellulosic waste into valuable chemical products. Xylanases are hydrolase enzyme that catalyzes the β-1,4 linkages in heteropolysaccharide xylan which ultimately yields xylose monomers Microbes mainly fungi are used to synthesize xylanase to catalyze xylan into it...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 14 September 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Kanti Prakash SharmaAbstractTannins are plant secondary metabolites and characterized as plant defensive molecules. They impose a barrier against phytopathogens invasion in plants and thus oppose diseases occurrence in them. Tannase is an enzyme known for its ability to degrade plant tannins. Important plant pathogens also possess tannase coding sequence in their genome. Researches on tannase are till date focused on its applications in animal nutrition, in bioremediation and in food industries etc. The informa...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: 5 January 2020Source: Journal of Molecular Structure, Volume 1199Author(s): Danyang Dong, Qizhe Li, Wenlong Hou, Haiquan ZhangAbstractA stable open-shell bay-bromine substitute perylene diimide anion radical π-oligomer was facilely synthesized in N,N′-dimethylformamide with K2CO3. The unusual π-oligomer showed wide absorption of 400–850 nm and the spacing for adjacent perylene core was 3.25 Å. Z-scan measurements exhibited that π-oligomer had high nonlinear optical character with βeff = −1.85 × 10−13 m/W, γeff = 1.025 × 10...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 13 September 2019Source: Life SciencesAuthor(s): Sajjad Ahmadpour, Seyed Jalal HosseinimehrAbstractBreast cancer deaths occur mainly because of poor diagnosis in early stages that lead to tumor metastasis in advanced stages. Developing a high-sensitive early-stage breast cancer diagnostic tool based on single photon emission computer tomography (SPECT) and positron emission tomography (PET) are urgent. There are several evidences to demonstrate the prominent roles of specific receptors overexpression in tumor initiation and progression of breast cancer. Targeting of specific receptor with...
Source: Life Sciences - Category: Biology Source Type: research
In this study, the poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was synthesized using Madhuca indica flower extract as cheaper carbon source by Ralstonia eutropha. The Influence of fermentation parameters such as incubation time, temperature, pH and inoculum size were studied on production of PHBV. The maximum production of PHBV (1.44 ± 0.016 g/L with yield of 49.4 %) was obtained at a temperature, pH, inoculum size and incubation time of 35 °C, 6, 5 % v/v and 48 h, respectively. The PHBV was characterized using nuclear magnetic resonance spectroscopy (NMR), Fourier tra...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
In this study, 120 plants were subjected to 0–4 °C climate chamber for 0–28 d with a weekly interval, morphology and structure changes of buds were studied with a scanning electron microscope (SEM) and paraffin sections during the dormancy process. Dormancy status was evaluated after being transferred to greenhouse for 30 d. Results showed that the diameter of the buds gradually expanded, along with continuous elongation of sepals, petals, stamens and carpels in the chilling accumulation process. Notably, dormancy release was marked with the establishment of xylem vessels in lateral vein of the petal....
Source: Plant Physiology and Biochemistry - Category: Biochemistry Source Type: research
More News: Complementary Medicine | Dermatology | Ginseng | PET Scan | Skin | Vitamins