Progressive Exercise Training Improves Maximal Aerobic Capacity in Individuals with Well-Healed Burn Injuries.

Progressive Exercise Training Improves Maximal Aerobic Capacity in Individuals with Well-Healed Burn Injuries. Am J Physiol Regul Integr Comp Physiol. 2019 Aug 21;: Authors: Romero SA, Moralez G, Jaffery MF, Huang M, Cramer MN, Romain N, Kouda K, Haller RG, Crandall CG Abstract Long term rehabilitative strategies are important for individuals with well-healed burn injuries. Such information is particularly critical because patients are routinely surviving severe burn injuries given medical advances in the acute care setting. The purpose of this study was to test the hypothesis that a 6-month community-based exercise training program will increase maximal aerobic capacity (V̇O2max) in subjects with prior burn injuries, with the extent of that increase influenced by the severity of the burn injury (i.e., percent body surface area burned). Maximal aerobic capacity (indirect calorimetry) and skeletal muscle oxidative enzyme activity (biopsy of the vastus lateralis muscle) were measured pre- and post-exercise training in non-injured control subjects (N = 11) and in individuals with well-healed burn injuries (N = 13, moderate body surface area burned; N = 20, high body surface area burned). Exercise training increased V̇O2max in all groups (control 15 ± 5 %; moderate body surface area 11 ± 3 %; high body surface area 11 ± 2 %; P < 0.05), though the magnitude of this improvement did not differ between groups (P = 0.7). Exercise trai...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - Category: Physiology Authors: Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research