Erythema with pustular folliculitis: A rare drug eruption induced by infliximab

Case reports on folliculitis as an adverse cutaneous drug reaction (ACDR) to tumor necrosis factor (TNF)-alpha inhibitors are sparse in the literature, and resolution with topical therapy has been reported. We here report 2 cases of ACDR to infliximab presenting as folliculitis, one of which required systemic therapies and the discontinuation of TNF-alpha inhibitor. Case 1: A 29-year-old male with Crohn ’s disease (CD) treated with infliximab for 7 years, in full remission, presented for evaluation of high fever, erythema with central blistering on the trunk, and pustules scattered on the whole body.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research