Frontal fibrosing alopecia: Histopathological and immunohistochemical study of the inflammatory infiltrate and the sebaceous gland receptors

Introduction: Frontal fibrosing alopecia (FFA) is a primary scarring alopecia characterized by a recession of the frontotemporal hairline and, frequently, alopecia of the eyebrows. The etiopathogenesis of FFA is unknown, but an autoimmune reaction mediated by T lymphocytes has been suggested. The characteristic localization, the predominance of postmenopausal women and the clinical stabilization with oral antiandrogenic drugs suggest that hormonal imbalance may play a pathogenic role.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research