Repository of genetic and clinical data from hidradenitis suppurativa patients in a subspecialty dermatology clinic

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the folliculopilosebaceous units. It is characterized by recurrent inflammatory nodules that may progress to draining sinuses with scar formation. HS often results in severe pain, disability, and disfigurement. It appears that genes play a role in HS, with an estimated 40% of patients having an affected first-degree family member. Research on a few families documents an autosomal dominant pattern of inheritance, but HS remains poorly understood without any large-scale genetic evaluations to date.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research