Sweet syndrome secondary to cervical cancer recurrence

Introduction: Sweet syndrome (SS), also known as febrile neutrophilic dermatosis is a clinical condition characterized by painful, tender, erythematous plaques and nodules, fever, neutrophilia and a diffuse mature neutrophilic infiltrate in the dermis. It can present as an idiopathic entity, associated with systemic drugs or as a paraneoplastic debut of underlying malignancy.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research

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Conclusion: This case of thyroid bed PG supports the idea that PG reflects a cutaneous phenotype encompassed in the spectrum of systemic neutrophilic diseases. Endocrinologists should be aware that thyroid bed PG involvement is an albeit rare differential diagnosis to consider in patients who had undergone thyroid surgery, especially with a history of PG. Introduction Papillary thyroid carcinoma (PTC), the main variant of differentiated thyroid carcinoma (DTC), is the most common thyroid cancer, accounting for 70–80% of all thyroid carcinomas and occurring predominantly in women, generally with a good prognos...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Though rare in cervical cancer patients, paraneoplastic syndrome usually presents with several endocrine and hormonal symptoms. Knowledge of the pathophysiology that underlies these abnormalities is beneficial to diagnosis and treatment. An interdisciplinary approach and test analysis prior to initiating specific treatment is recommended, though prognosis appears poor in advanced cases. Key Clinical MessageThough rare in cervical cancer patients, paraneoplastic syndrome usually presents with several endocrine and hormonal symptoms. Knowledge of the pathophysiology that underlies these abnormalities is beneficial to diagnos...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
Dermatomyositis (DM) is often found in conjunction with malignant tumors such as lung, cervical, and breast cancer. However, the association with intrahepatic cholangiocarcinoma (ICC) is extremely rare. Moreover, to our knowledge, there have been no previous reports of DM discovered because of exacerbation of DM. Our case was a 44-year-old female with dry cough, myalgia, and arthralgia. We performed hepatic resection for intrahepatic ICC. She was diagnosed with DM, and combination treatment with prednisolone and tacrolimus was started. During outpatient visits, her symptoms worsened, and she was hospitalized due to deterio...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
We report a rare case of paraneoplastic Sweet ’ s syndrome associated with the diagnosis of cervical cancer.
Source: Anais Brasileiros de Dermatologia - Category: Dermatology Source Type: research
CONCLUSIONS: PON is relative rare, with a predominance of bilateral involvement and more with a poor visual prognosis. Paraneoplastic antibody testing can contribute to the diagnosis of PON, distinct from other types of optic neuropathies, which can help doctors to find the primary cancer earlier to guide further treatment. PMID: 30021813 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
Authors: Fukuda H, Tanaka A, Hirashima Y, Ito I Abstract Lambert-Eaton myasthenic syndrome (LEMS) is most commonly associated with small cell lung carcinoma, while it is rarely associated with gynecological and breast carcinoma. We herein report a case of LEMS associated with synchronous double cancer, which was a combination of small cell carcinoma of the cervix and breast carcinoma. The early diagnosis and treatment of LEMS are important for achieving a good outcome. The possibility of accompanying paraneoplastic neurological syndrome must be sufficiently considered in gynecology and breast cancer patients. To ou...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conclusions:CP is both diagnostically and therapeutically useful in malignant and non-malignant CNS disease. The procedure is well-tolerated and can alter clinical management. CP should be considered in patients for whom LP is contraindicated or non-diagnostic.Disclosure: Dr. Umemura has nothing to disclose. Dr. Panageas has nothing to disclose. Dr. Boire has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Neuro-oncology: Brain and CNS Metastases Source Type: research
Objective:We evaluated if longitudinally-extensive cervical cord lesions extending to or accompanied by Area Postrema (AP) lesions on MRI are specific for Neuromyelitis Optica Spectrum Disorder (NMOSD).Background:Prior studies have suggested spinal cord lesions extending to the AP are specific for NMOSD. However, in our practice we have encountered numerous non-NMOSD long myelopathies extending to the AP.Design/Methods:We reviewed the records and MRI’s of Mayo Clinic patients with cervical spinal cord lesions from our AQP4-IgG seropositive NMOSD myelitis (1996–2014) and long myelopathy database (1996–2016...
Source: Neurology - Category: Neurology Authors: Tags: Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis, and Optic Neuritis B Source Type: research
Conclusion: Here, we present a rare case of DM caused by non-hepatitis-associated advanced HCC with colonic perforation. The cause of colonic perforation is still unclear. This case demonstrates the need to carefully monitor abdominal pain in DM patients as symptoms can be masked by steroid therapy.Case Rep Oncol 2016;9:547 –553
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
Authors: Erdener SE, Vural A, Temucin CM, Ozdamar SE, Nurlu G, Varli K, Dericioglu N Abstract Sensory neuronopathy is a well-established presentation in paraneoplastic neurological syndromes that is mostly associated with small cell lung cancer and anti-Hu antibodies. Motor neuronopathy, on the other hand, is an extremely rare observation in this syndrome. A 56-year-old man presented with asymmetric brachial diparesis and sensory ataxia. Electrophysiological studies revealed sensory ganglionopathy and progressive anterior horn degeneration in cervical segments. Small cell lung carcinoma with associated anti-Hu anti...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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