Inherited susceptibility to miscarriage: a nested case-control study of 31565 women from an intergenerational cohort

Miscarriage can be a devastating outcome for couples and most miscarriages are unexplained. Many adverse obstetric outcomes are thought to be inherited such as pre-eclampsia, preterm birth and growth restriction. It is possible these conditions could share similar pathophysiological mechanisms with miscarriage such as endothelial dysfunction. Therefore, it was hypothesised that there could be a susceptibility to miscarriage transmitted from mother to daughter.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Original Research: Gynecology Source Type: research