Thermal behavior of inosine 5’-monophosphate complexes with cobalt(ii), nickel(ii), copper(ii) and cadmium(ii) cations

Publication date: Available online 17 August 2019Source: Thermochimica ActaAuthor(s): J.H.F. de Jesus, M.S. Souza, J.A. Ellena, E.T.G. CavalheiroABSTRACTInteraction of nucleotides and metals has been largely studied since they have biological importance. Divalent complexes with cobalt(II) (IMP-Co), nickel(II) (IMP-Ni), copper(II) (IMP-Cu) and cadmium(II) (IMP-Cd) with inosine 5′-monophosphate have been characterized by elemental analysis and submitted to thermogravimetry (TG), differential thermal analysis (DTA), differential scanning calorimetry (DSC) and thermogravimetry coupled to infrared spectroscopy (TG-FTIR). Cadmium(II) complex with inosine 5’-monophosphate had also its crystalline structure elucidated by single-crystal X-ray diffraction. Elemental analysis revealed the isolated metal complexes had the proportion of 1:1. The thermal stability order was: IMP-Co (193 °C) = IMP-Cd (193 °C) < IMP-Ni (206 °C) < IMP-Cu (219 °C), after dehydration. Cd2+ ions present octahedral coordination with an IMP ligand through nitrogen donor atom and the remaining coordinating sites through five water molecules. The crystal packing assembly has a similar distribution to the DNA molecule, with alternation between the atoms leading to a helical conformation.

Source: Thermochimica Acta - August 18, 2019 Category: Chemistry Source Type: research