Transcriptional Profiling of Stem Cells: Moving from Descriptive to Predictive Paradigms

Publication date: 13 August 2019Source: Stem Cell Reports, Volume 13, Issue 2Author(s): Christine A. Wells, Jarny ChoiTranscriptional profiling is a powerful tool commonly used to benchmark stem cells and their differentiated progeny. As the wealth of stem cell data builds in public repositories, we highlight common data traps, and review approaches to combine and mine this data for new cell classification and cell prediction tools. We touch on future trends for stem cell profiling, such as single-cell profiling, long-read sequencing, and improved methods for measuring molecular modifications on chromatin and RNA that bring new challenges and opportunities for stem cell analysis.
Source: Stem Cell Reports - Category: Stem Cells Source Type: research