The Ability of Ultrasonic Backscatter Parametric Imaging to Characterize Bovine Trabecular Bone.

The Ability of Ultrasonic Backscatter Parametric Imaging to Characterize Bovine Trabecular Bone. Ultrason Imaging. 2019 Jul 16;:161734619862190 Authors: Li Y, Li B, Li Y, Liu C, Xu F, Zhang R, Ta D, Wang W Abstract The ultrasonic backscatter technique holds the promise of characterizing bone density and microstructure. This paper conducts ultrasonic backscatter parametric imaging based on measurements of apparent integrated backscatter (AIB), spectral centroid shift (SCS), frequency slope of apparent backscatter (FSAB), and frequency intercept of apparent backscatter (FIAB) for representing trabecular bone mass and microstructure. We scanned 33 bovine trabecular bone samples using a 7.5 MHz focused transducer in a 20 mm × 20 mm region of interest (ROI) with a step interval of 0.05 mm. Images based on the ultrasonic backscatter parameters (i.e., AIB, SCS, FSAB, and FIAB) were constructed to compare with photographic images of the specimens as well as two-dimensional (2D) μ-CT images from approximately the same depth and location of the specimen. Similar structures and trabecular alignments can be observed among these images. Statistical analyses demonstrated that the means and standard deviations of the ultrasonic backscatter parameters exhibited significant correlations with bone density (|R| = 0.45-0.78, p < 0.01) and bone microstructure (|R| = 0.44-0.87, p < 0.001). Some bovine trabecular bone microstructure parameters were...
Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research