Animal to human translation: a systematic scoping review of reported concordance rates

Drug development is currently hampered by high attrition rates; many developed treatments fail during clinical testing. Part of the attrition may be due to low animal-to-human translational success rates; so-c...

Source: Journal of Translational Medicine - July 15, 2019 Category: Research Authors: Cathalijn H. C. Leenaars, Carien Kouwenaar, Frans R. Stafleu, Andr é Bleich, Merel Ritskes-Hoitinga, Rob B. M. De Vries and Franck L. B. Meijboom Tags: Review Source Type: research