Medical News Today: How can rheumatoid arthritis affect the jaw?

Rheumatoid arthritis (RA) can affect the jaw joint, causing tenderness and swelling. In this article, we look at the symptoms and treatments for RA in the jaw.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news

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This study establishes adjuvant-induced arthritis (AIA) mouse models and explores the anti-inflammatory efficacy of QAW in AIA mice. To enhance the targeting, responsiveness, and efficacy of QAW to inflammation, QAW (Q) is modified with a cell penetrating peptide (T), a matrix metalloproteases-2/9 (MMP-2/9) digestive peptide (M), and an inflammation targeting peptide-RGD (R). The designed RMTQ demonstrates enhanced delivery to cytoplasm, higher reduction of pro-inflammatory factors, and better efficacy than QAW. The anti-inflammatory efficacy of RMTQ is similar to that of DEX in this study whereas RMTQ treatment shows a hi...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Authors: Wang P, Mao YM, Liu LN, Zhao CN, Li XM, Pan HF Abstract A growing body of data suggests that semaphorins are involved in both normal and pathological immune responses, as well as autoimmune pathologies. To investigate the plasma semaphorin 3A (Sema3A) and semaphorin 7A (Sema7A) levels in systemic lupus erythematosus (SLE) patients and their correlation with clinical manifestations and laboratory indexes, a two-step method was applied. First, 80 SLE patients and 80 healthy controls were recruited for comparing serum Sema3A and Sema7A concentrations. Second, 40 rheumatoid arthritis (RA) patients and 40 sj&ou...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
In conclusion, osteoporosis is prevalent among RA patients, as a part of a complex transformation of body mass composition, involving BMI and fat mass. The novel QUS scanning technique was able to replicate the results of the established DXA measurement of BMD and is potentially suitable for screening wide populations for osteoporosis. PMID: 31410123 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Find out how the safety profile for abatacept compared with that of other DMARDs for rheumatoid arthritis.Arthritis Research &Therapy
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Rheumatology Journal Article Source Type: news
ConclusionReported cases of PTRCT and its surgical repair have both increased substantially over time. Approximately 11.70% of patients with PTRCT undergo either open or arthroscopic procedure as a means of surgical repair. With the growing popularity of arthroscopic procedures for rotator cuff repair, further investigation should be performed to analyze trends and risk factors for PTRCT, a seemingly underrepresented orthopedic condition.
Source: Journal of Orthopaedics - Category: Orthopaedics Source Type: research
Conclusion. There was no difference in TBL, intraoperative bleeding, and operation time, but HBL were higher in RA patients particularly in long-segmental operation. Steinbroker classification, DMARDs, the change of Hb, and allogeneic blood transfusion were independent risk factors for HBL in RA patients. Level of Evidence: 3
Source: Spine - Category: Orthopaedics Tags: OCCUPATIONAL HEALTH/ERGONOMICS Source Type: research
Condition:   Rheumatoid Arthritis Interventions:   Drug: SKI-O-703;   Drug: Placebo Sponsor:   Oscotec Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: IL-34 may indirectly contribute to angiogenesis by promoting the production of VEGF and HIF-1α and participate in the pathogenesis of RA. PMID: 31401905 [PubMed - as supplied by publisher]
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Conditions:   Rheumatoid Arthritis;   Synovial Disorder;   Arthrosis Intervention:   Procedure: Joint puncture Sponsor:   University Hospital, Bordeaux Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Cardiovascular Diseases;   Arthritis, Rheumatoid Interventions:   Drug: Atorvastatin;   Drug: Colchicine Sponsor:   Hospital Central  " Dr.  Ignacio Morones Prieto " Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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