Methods for Assessing the Effects of LXR Agonists on Macrophage Bacterial Infection.

Methods for Assessing the Effects of LXR Agonists on Macrophage Bacterial Infection. Methods Mol Biol. 2019;1951:135-141 Authors: Glaría E, Matalonga J, Valledor AF Abstract Macrophages are phagocytic cells that actively engulf and kill microorganisms within a specialized phagolysosomal system. Several pathogenic bacteria, however, actively co-opt host mechanisms and escape from microbial digestion to establish intracellular replication within macrophages. This chapter highlights detailed protocols to measure the effects of the LXR pathway on bacterial infection of murine bone marrow-derived macrophages. PMID: 30825149 [PubMed - indexed for MEDLINE]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research