Tumour-induced Osteomalacia Secondary to Intracranial Tumours - Report of 2 Cases.

Tumour-induced Osteomalacia Secondary to Intracranial Tumours - Report of 2 Cases. J Assoc Physicians India. 2019 Apr;67(4):85-86 Authors: Gunawat PV, Shaikh ST, Deopujari CE Abstract Tumor induced osteomalacia (TIO) is a paraneoplastic syndrome which is mostly caused by a phosphaturic mesenchymal tumour mixed connective tissue variant (PMTMCT). These tumours do not have any specific site predilection but their presence in cranial compartment is very rare. Two cases of TIO secondary to phosphaturic mesenchymal tumour at the skull base are described ahead, one of which was in the posterior fossa and the other in middle cranial fossa. Early diagnosis and complete excision of PMT is essential in preventing morbidity secondary to osteomalacia. This case report stands distinct in highlighting a rare site of a phosphaturic mesenchymal tumour and the need to keep a high index of suspicion in cases of TIO especially wherein localization of the tumour is unsuccessful. PMID: 31299850 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research