Losartan Induced Acute Urticaria.
Losartan Induced Acute Urticaria. J Assoc Physicians India. 2019 Apr;67(4):93 Authors: Srivastava A, Mathur AD PMID: 31299855 [PubMed - in process]
Background: Psoriasis, psoriatic arthritis, atopic dermatitis (AD), hidradenitis suppurativa (HS) and chronic urticaria (CU) are associated with sleep disturbances (SD). Validated, disease-specific instruments are needed to assess SD in these populations. This work focuses on the development of the ‘PsO Sleepy-Q’ for psoriasis and ‘PsA Sleepy-Q’ for psoriatic arthritis.
Introduction: Hypereosinophilic syndrome (HES) is a rare multisystem disorder characterized by blood eosinophilia ≥1500/mm3 for more than 6 months, lack of evidence for parasitic, allergic, or other known causes of eosinophilia and development of organ dysfunction and/or damage.1 Cutaneous involvement varies from commonly seen manifestations like nonspecific rash, urticaria, angioedema, pruritic papules to le ss common manifestations like mucosal ulcers, eosinophilic vasculitis, erythema annulare centrifugum and erythroderma.
We present two cases of teen-onset UP highlighting our experience. Our first case represents a 16-year-old female presenting with numerous scattered ∼5 mm or smaller orange-brown macules extending over the chest, neck, abdomen, back, and upper extremities with a positive Darier’s sign.
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterized by a rapid development of multiple sterile pustules arising within edematous erythema, with fever and leucocytosis. In 90 % of cases, it is caused by drugs, most frequently antibiotics. AGEP is rare, with an estimated incidence of one to five patients per million per year, and occurs most frequently in adults. A 1-year-old child was admitted to our hospital with a presentation of fever and eruption first compatible with urticaria multiforme, most probably from an infectious cause.
We present a case of new onset UP in an adult masquerading as simple lentigines. Unlike in children, in adults the presence of UP should prompt a thorough evaluation for systemic mastocytosis (SM) as the literature reports that 90-95% cases of adult-onset cutaneous mastocytosis are diagnosed with SM. A 31-year-old male without significant past medical history complains of ‘darkening spots’ on his left foot and trunk.
The objective of this document is to obtain consensus on the treatment of CU patients among dermatology and allergology specialists in Andalusia, on optimization in the management of patients with a multidisciplinary and agreed-upon approach, representing Andalusian provinces in order to unify SCU patient management and treatment criteria according to the latest European guidelines that have been published on SCU/CIU patient management, experts ’ recommendations and real-world experience.
Phospholipase-C γ2-associated antibody deficiency and immune dysregulation (PLAID) is a rare, genetically complex immunodeficiency syndrome characterized by cold urticaria, noninfectious cutaneous granulomas, autoimmunity, and humoral immune deficiency. The syndrome was only recently discovered after linkage analy sis of three families with lifelong cold-induced urticaria and variable immune defects revealed dominantly inherited genomic deletions resulting in the temperature-sensitive constitutive activation of PLCG2, which encodes a signaling molecule expressed in B cells, natural killer cells, and mast cell s.
Introduction: Urticaria-like follicular mucinosis (ULFM) is a rare, primary follicular mucinosis (PFM). It was first described in 1980. Only ten cases have been described in the literature. Herein, we report a case of ULFM.
Atopic dermatitis (AD) and bullous pemphigoid (BP) are inflammatory skin diseases in which patients often report intense pruritus and significant quality of life (QOL) impact. Although they have differences in classical presentation (eczematous eruption versus urticaria and blisters) and population characteristics (young-to middle aged persons vs. elderly), early stages of BP can appear similar to AD clinically and histologically. We wanted to explore whether there were significant similarities or differences in pruritus characteristics and QOL impact.
Endless summer. Whoever came up with that phrase must not have had kids in grade school. One minute you’re signing your little one up for day camp, the next you’re at Target for some last-minute back-to-school shopping. On the other hand, after cleaning up yet another summer-activity-related mess, you might be muttering to yourself, when do they go back to school again? Amidst all the summer hustle and bustle (and hopefully a few quiet moments for Mom), it may be easy for you and your child to forget that they’ll be back behind a school desk before you know it. That’s probably for the best. School m...