The rtPA increases MMP-9 activity in serum during ischaemic stroke.

CONCLUSIONS: Thrombolysis applied for IS treatment increases MMP-9 activity in serum, however, rtPA does not facilitate the conversion of pro-MMP-9 into the active form. Our results also suggest the involvement of MMP-3 to the biochemical processes occurring during acute phase of IS. PMID: 25440008 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25440008?dopt=Abstract

Source: Neurologia i Neurochirurgia Polska - December 8, 2014 Category: Neurology Authors: Gołąb P, Boguszewska-Czubara A, Kiełbus M, Kurzepa J Tags: Neurol Neurochir Pol Source Type: research

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