Lateral extra-articular tenodesis reduces hamstring autograft

(American Orthopaedic Society for Sports Medicine) The addition of lateral extra-articular tenodesis to a hamstring autograft in knee surgery in young active patients significantly reduces graft failure and persistent anterolateral rotatory laxity at two years post operatively. The research, presented at the Annual Meeting of the American Orthopedic Sports Medicine Society, received the O'Donoghue Sports Injury Award.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Purpose of review Orthotopic heart transplantation (OHT) significantly improves morbidity and mortality in patients with end-stage heart disease. Despite advances in surgical technique, immunosuppressive therapies, and patient monitoring, long-term risk of arrhythmias and sudden cardiac death (SCD) in the denervated heart remains unchanged. Recent findings SCD is responsible for approximately 10% of all posttransplant deaths with a pooled incidence rate of 1.30 per 100 person years and is strongly associated with cardiac allograft vasculopathy (CAV). Risk factors for SCD and CAV include higher donor age, younger recip...
Source: Current Opinion in Cardiology - Category: Cardiology Tags: CARDIAC FAILURE: Edited by Rebecca Cogswell and Gene Kim Source Type: research
The development of biomaterials for orthopedic applications is a crowded space with several large and small companies designing innovative materials. One approach is the use of these materials to deliver therapeutic proteins that enhance healing. The...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Medicine Nanomedicine Orthopedic Surgery Source Type: blogs
Condition:   Chronic Allograft Injury Interventions:   Drug: UCB7858;   Drug: Placebo Sponsor:   UCB Biopharma SRL Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: The combination of PRF plus bone filler promotes bone neoformation, increased trabecular bones, and improved healing times; however, after 6 months of monitoring, the results were not significantly different with the groups that did not use the PRF in the procedure of maxillary sinus floor lift with lateral window technique. Regarding the preservation of alveolar ridge the different studies are not conclusive: some indicate that the mixture of a concentrate with a bone filling seems to improve the volumetric proportions; however, other studies report bone loss in width and even greater degree of inflammation.
Source: Revista Espanola de Cirugia Oral y Maxilofacial - Category: ENT & OMF Source Type: research
Immunotherapy, Ahead of Print.
Source: Immunotherapy - Category: Allergy & Immunology Authors: Source Type: research
In this study, the clinical outcomes of horizontal ridge augmentation using half-columnar bone grafts from the ramus (group I: 27 patients, 32 implants) versus rectangular bone grafts from the symphysis (group II: 19 patients, 27 implants) were compared; grafts were combined with organic bovine bone and collagen membrane. Cone beam computed tomography images were obtained preoperatively, immediately after restoration (baseline), and 1 year after loading. Four months after grafting, horizontal bone resorption at the alveolar crest did not differ significantly between the two groups (P=0.291).
Source: International Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Randomised Clinical Trial, Pre-Implant Surgery Source Type: research
In open wounds a peripheral nerve may be damaged and part of it can be defective. When tension-free suturing is not possible, then the nerve tissue defect is bridged with a graft that acts as a conduit for regenerating the nerve axons while providing the necessary components for the nerve regeneration process [1]. In clinical practice, autologous nerve transplantation is considered to be the main method of bridging neural defects. The neural grafting method has some disadvantages, most notably the morbidity of the donor area and the need for more than one operation.
Source: Injury - Category: Orthopaedics Authors: Source Type: research
Background: Following transplant, cancer is a leading cause of morbidity and mortality. Human leukocyte antigen-G (HLA-G) – an immune checkpoint molecule – reduces allograft rejection by dampening host immune responses. Reports suggest malignant cells utilize HLA-G to evade the immune system and promote cancer development. Our objective was to evaluate HLA-G donor-recipient polymorphism matching and development of cancer following heart transplant. Methods: Recipients (n=251) and corresponding donors (n=196) were genotyped retrospectively to identify HLA-G polymorphisms in the 5’regulatory (–725, &n...
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Authors: Schaefer B, Beier JP, Ruhl T Abstract Skeletal muscle represents the largest mass of tissue in the body and is essential for motion and posture. Traumatic injury, tumor ablation, prolonged denervation or genetic defects lead to skeletal myopathies. The loss of muscle function or its regenerative properties often results in pain, deformity, and joint malfunction. The regenerative capacity of skeletal muscles depends on adult muscle stem cells, the so-called satellite cells; however, the population of these myogenic precursors, and thus their potential to restore large muscle tissue defects, is strongly limi...
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research
ConclusionsAlthough the aetiology of SONK remains unknown, there are many treatment options, and the choice of the most suitable one is challenging. We think that subchondroplasty may be one of the effective methods.
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
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