Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment.

CONCLUSION: Nature products, especially marine ones are potential resources for CDK1 inhibitors development. The findings of CDK2 allosteric inhibitors open an avenue to the discovery of novel selective CDK1 or other CDKs allosteric inhibitors.
PMID: 31241436 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - June 25, 2019 Category: Chemistry Authors: Mou J, Chen D, Deng Y Tags: Med Chem Source Type: research