GSE133217 Differenatiation of miRNA expression in PBMCs (peripheral blood mononuclear cells)

Contributors : Caiyan Zhang ; Yufeng ZhouSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensTo determine miRNA transcribed during the PBMCs, we have employed whole genome microarray expression profiling as a discovery platform to identify miRNA expression in PBMCs donated by T1DM (type 1 diabetes mellitus) patients and healthy volunteers.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Source Type: research

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Publication date: September 2019Source: Biomedical Signal Processing and Control, Volume 54Author(s): Shadi Khodakaramzadeh, Yazdan Batmani, Nader MeskinAbstractArtificial pancreas (AP) systems perform automated insulin delivery to subjects with type 1 diabetes mellitus (T1DM). In this paper, a nonlinear suboptimal controller is designed to make a trade-off between the elimination of hypoglycemia events and the limitation of postprandial hyperglycemia. All the in silico simulations are performed using the distribution version of the UVA/Padova type 1 diabetes (T1D) simulator. The proposed nonlinear AP system is based on an...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Authors: Kumar S, Gupta A, Sameja P, Patel I, Gupta S Abstract Diabetes mellitus a disease with various macro and micro vascular complications due to its various metabolic dysregulations, is well known to involve lungs in long run in both type 1 and 2 diabetes mellitus, causing tremendous burden on health care system. Common simple lung function tests alone are likely to underestimate the prevalence and degree of lung dysfunction in diabetes, but newer noninvasive tests of lung mechanical function provide a more sensitive assessment of peripheral airway function, hence by establishing a marker and risk factors for ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Authors: Wang Y, Han P, Wang M, Weng W, Zhan H, Yu X, Yuan C, Shao M, Sun H Abstract Many patients with type 1 diabetes mellitus suffer from progressive diabetic kidney disease (DKD). The progression of DKD is largely attributed to mitochondrial dysfunction, with key contributions from mitochondrial reactive oxygen species. Recent studies have revealed that the antimalarial drug artemether has antidiabetic effects. To identify potential effects on type 1 DKD in the present study, mice with streptozotocin-induced diabetes were treated with artemether. Treatment reduced urinary excretion of albumin and tubular injury...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Authors: Bhagat AK, Bhardwaj H, Bhardwaj BL, Goyal S, Jaura S, Jain P Abstract Introduction: Cataract represents one of the most frequent eye complications in type 1 DM and type 2 DM patients; contrarily, acute cataract in young diabetic patients occurs very rarely. Only few cases with acute bilateral cataract - all relatively shortly after the diagnosis of type 1 DM have been reported. It can affect visual acuity from slight visual impairment to complete blindness. Although usually associated with chronic hyperglycaemia, it may also occur on rapid restoration of euglycaemia.1 Early detection of diabetes and adequa...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Classically, people with type 1 diabetes mellitus T1D present with several weeks of osmotic symptoms (polyuria and polydipsia), fatigue and weight loss that, in the absence of treatment, progress rapidly towards diabetic ketoacidosis (DKA) [1]. This presentation is seen most frequently in children but symptoms and signs can be variable [2]. In adults, T1D may present even with appreciable residual insulin secreting capacity [3,4]. After diagnosis and initiation of insulin treatment, there may be a period of temporary restoration of β-cell function that can last from months to years [5,6].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
Conditions:   Diabetes Mellitus, Type 1;   Diabetes Mellitus Interventions:   Drug: Lantus Solostar, 100 Units/mL Subcutaneous Solution;   Drug: Insulin RinGlar, 100 Units/mL Subcutaneous Solution Sponsor:   Geropharm Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This article is protected by copyright. All rights reserved. PMID: 31314914 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Pharmacology and Physiology - Category: Drugs & Pharmacology Authors: Tags: Clin Exp Pharmacol Physiol Source Type: research
The study aimed to assess the prevalence of hypoglycaemia in subjects with type 1 diabetes (T1D) attending a public health tertiary diabetes clinic in Durban, South Africa.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
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