A new ex vivo human oral mucosa model reveals that p38MAPK inhibition is not effective to prevent autoantibody-induced mucosal blistering in pemphigus.
CONCLUSION: In contrast to human epidermis, PV-IgG and AK23 induced blisters and desmosome ultrastructural changes in labial mucosa via a mechanism not dependent on p38MAPK. This article is protected by copyright. All rights reserved.
PMID: 31218663 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Egu DT, Sigmund AM, Schmidt E, Spindler V, Walter E, Waschke J Tags: Br J Dermatol Source Type: research