A new ex vivo human oral mucosa model reveals that p38MAPK inhibition is not effective to prevent autoantibody-induced mucosal blistering in pemphigus.

CONCLUSION: In contrast to human epidermis, PV-IgG and AK23 induced blisters and desmosome ultrastructural changes in labial mucosa via a mechanism not dependent on p38MAPK. This article is protected by copyright. All rights reserved. PMID: 31218663 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research