Modeling Embryonic Cleavage Patterns.

Modeling Embryonic Cleavage Patterns.
Methods Mol Biol. 2019;1920:393-406
Authors: Ershov D, Minc N
Abstract
The division patterns of early invertebrate and vertebrate embryos are key to the specification of cell fates and embryo body axes. We here describe a generic computational modeling method to quantitatively test mechanisms which specify successive division position and orientation of eggs and early blastomeres in 3D. This approach should serve to motivate and guide future experimental work on the mechanisms controlling early embryo morphogenesis.
PMID: 30737705 [PubMed - indexed for MEDLINE]

Source: Mol Biol Cell - June 20, 2019 Category: Molecular Biology Authors: Ershov D, Minc N Tags: Methods Mol Biol Source Type: research