[Trauma-Induced Coagulopathy: Pathophysiology and Management].
[Trauma-Induced Coagulopathy: Pathophysiology and Management].
Anasthesiol Intensivmed Notfallmed Schmerzther. 2019 Jun;54(6):413-423
Authors: Schlömmer C, Meier J
Abstract
Persistent, uncontrolled bleeding after trauma is one of the leading causes of fatalities in patients with severe injuries. 40% of trauma deaths are associated with massive haemorrhage. Hypoperfusion due to major loss of blood volume leads to tissue damage. In combination with acidosis and hypothermia, a generalized immune response with activation of coagulation is triggered. This leads to trauma-induced coagulopathy. A suitable, early treatment might lead to a significant reduction in morbidity and mortality.
PMID: 31212332 [PubMed - in process]
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - Category: Intensive Care Authors: Schlömmer C, Meier J Tags: Anasthesiol Intensivmed Notfallmed Schmerzther Source Type: research