The proportion of nuclear mature oocytes affects ooplasmic competence of metaphase-II in relation to implantation and live birth with ICSI

ConclusionsHigh proportion of immature sibling oocytes (GV, MI) in the retrieved cohort affects the fertilization rate and embryo developmental competence of the mature (MII) inseminated oocytes. These findings support the notion that in addition to nuclear maturity, ooplasmic and membrane maturity are required for embryo developmental competence of MII oocytes retrieved. These findings may provide guidance toward superovulation protocols aimed at achieving a greater proportion of MII oocytes leading to higher fertilization rates and better pregnancy outcomes.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research