Combination of LIM-kinase 2 and Jun amino-terminal kinase inhibitors improves erectile function in a rat model of cavernous nerve injury

To determine if combined administration of LIMK2 and JNK inhibitors in a rat model of ED induced by cavernosal nerve (CN) injury could restore erectile function by suppressing both cavernosal apoptosis and fibrosis via rectification of molecular pathways related to the structural alterations.

Source: Urology - June 12, 2019 Category: Urology & Nephrology Authors: Soo Woong Kim, Junghoon Lee, Juhyun Park, Ji Sun Chai, Sohee Oh, Jae-Seung Paick, Min Chul Cho Source Type: research