Diagnostic accuracy of T2 biomarkers for the prediction of airway eosinophilia in treated smoking asthmatics with loss of asthma control

Publication date: Available online 13 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Evgenia Papathanasiou, Petros Bakakos, Georgios Hillas, Polyxeni Ntontsi, Myrto Blizou, Konstantinos Kostikas, Nikolaos Koulouris, Spyros Papiris, Stelios Loukides
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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ConclusionsAnxiety, depression and asthma control (specially patient-rated asthma control) were important independent predictors of asthma HRQoL, and all of them should therefore be considered in interventions to improve HRQoL in asthmatic patients.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Babies with eczema have a high risk of developing asthma, food allergies and hay fever later in life, but that a " soak and seal " method of moistening a baby's skin can help prevent cracks from the condition.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
CONCLUSIONS: CRSwNP patients have significantly lower HRQoL compared with population norms. The impact is greater in patients with greater disease severity, comorbidities, or refractory disease. PMID: 31318362 [PubMed - as supplied by publisher]
Source: Rhinology - Category: ENT & OMF Tags: Rhinology Source Type: research
Asthma control changes over time and many factors contribute to this variability. Environmental exposures such as seasonal allergen fluctuations, second-hand tobacco exposure, and viral upper respiratory tract infections (RTI) are just a few of the known triggers of lability 1. In addition, host factors such as inhaler technique and co-morbid conditions including atopic diseases, obesity, and acid reflux can also contribute to this changeability. During times of lability, overzealous intervention can lead to overuse of oral corticosteroids (OCS) and healthcare visits, while delayed treatment can lead to severe exacerbation...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research
Chronic spontaneous urticaria (CSU), a common vascular skin disease with high incidence (approximately 0.5% to 1%) and recurrent attacks, is one of the skin diseases that seriously affect the quality of patients ’ life1. Some CSU patients have resistance to treatment. About 45%-60% of patients could be effectively treated by antihistamines. Studies demonstrate that histamine and other vasoactive substances, released by mast cell degranulation, can ultimately lead to increase the permeability of human derm al microvascular endothelial cells (HDMECs)2, which is considered to be the central link in the pathogenesis of CSU.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Our literature review found that over- or under-perception of airway obstruction is an important and often overlooked factor in the management of asthma, and should be assessed whenever possible
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
It's not clear which inhaled corticosteroids and delivery devices have the least adverse impact on growth in children with persistent asthma, a systematic review concludes.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news
Authors: Sullivan PW, Kavati A, Ghushchyan VH, Lanz MJ, Ortiz B, Maselli DJ, LeCocq J Abstract Objective: To estimate the health-related quality of life (HRQoL) and health utilities among asthma patients with and without comorbid allergies in a managed care population. Methods: This was a retrospective analysis of patient survey responses and pharmacy claims from the Observational Study of Asthma Control and Outcomes (OSACO). Patients ≥12 years-old with persistent asthma received four identical surveys between April-2011 and December-2012. The presence of allergy was identified by a positive response to a survey...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
AbstractPurpose of ReviewThis review aimed to introduce the regulations management and current situations of drug safety evaluation in China.Recent FindingsThe nationwide implementation of good laboratory practice and good clinical practice guarantees the quality of pre-marketing drug safety evaluation. In recent years, post-marketing drug safety monitoring is changing from passive mode to the combination of active and passive monitoring. A national adverse drug reaction monitoring sentinel alliance has been created to actively identify, report, and evaluate adverse reactions, with more than 1.4 million cases reported in 2...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
This study aims to evaluate public perceptions of need and benefit of providing local pollen information. Individuals aged 18  years and older were contacted through AusPollen Smartphone Apps (Brisbane, Sydney, Canberra and Melbourne), Australian Society for Clinical Immunology and Allergy, Asthma Australia and social media. A pilot questionnaire was developed in consultation with partner organisations, including select q uestions drawn from the National Young People and Asthma Survey. The questionnaire consisted of four sections: participant demographics, allergic rhinitis and asthma symptoms, symptom management and ...
Source: Aerobiologia - Category: Environmental Health Source Type: research
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