Role of the Innate Cytokine Storm Induced by the Influenza A Virus

Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research

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Publication date: Available online 10 December 2019Source: Microbial PathogenesisAuthor(s): Mohsan Ullah Goraya, Fozia Zaighum, Nelam Sajjad, Faisal Rasheed Anjum, Irfan Sakhawat, Sajjad ur RahmanAbstractInfluenza viruses cause mild to severe infections in animals and humans worldwide with significant morbidity and mortality. Infection of eukaryotic cells with influenza A viruses triggers the induction of innate immune system through the interaction between pattern recognition receptors (PRRs) and pathogen associated molecular patterns (PAMPs), which culminate in the induction of interferons (IFNs). Consequently, IFNs bind...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 9 December 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Qingtao Liu, Jing Yang, Xinmei Huang, Yuzhuo Liu, Kaikai Han, Dongmin Zhao, Lijiao Zhang, Yin LiAbstractAvian influenza subtype H9N2 infection is a mild but highly contagious disease that is associated with a decrease in the efficacy of vaccine interventions, and an increase in susceptibility to secondary infections in poultry. However, the immune evasion mechanism of H9N2 avian influenza viruses (AIVs) in chickens is poorly understood. Dendritic cells (DCs) are immune cells of major importance, involved in innate ...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
S. Murakami et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
D. Chu et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Influenza activity is widespread or regional in more than half the country weeks earlier than last year, according to the CDC.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Infectious Diseases News Source Type: news
Bone Marrow Transplantation, Published online: 10 December 2019; doi:10.1038/s41409-019-0770-3Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
AbstractPurpose of ReviewIn the last year, an increasing number of studies have reported on methicillin-resistantStaphylococcus aureus (MRSA) transmission in Africa and Asia and in migrant workers. We reviewed original research on occupational health and safety of animal workers published from January 1, 2018, through June 30, 2019, with a targeted focus on infectious disease studies published in these populations.Recent FindingsStudies focused on occupational exposures to infectious agents, dust and allergens, pesticides, and occupational injury. Research on zoonotic MRSA used whole genome –sequencing technologies t...
Source: Current Environmental Health Reports - Category: Environmental Health Source Type: research
Flu season in the U.S. is off to an early start—which means a virulent winter may be impending. Influenza activity has been higher than normal for four weeks in a row, which many experts consider the official mark of flu season. As of the week ending Nov. 30, 3.5% of visits to health care providers nationwide were related to influenza-like illness, according to the U.S. Centers for Disease Control and Prevention (CDC). Already, the country has seen about 1.7 million cases of the flu, 16,000 flu-related hospitalizations and 910 flu-related deaths, the CDC says. Six children have died so far. So far this year, flu act...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease Source Type: news
AbstractObjectivesPneumococcal and influenza vaccination rates have been suboptimal in studies of immunosuppressed patients. We aimed to assess barriers to and increase rates of 23-valent pneumococcal polysaccharide vaccine (PPSV23) and influenza vaccination in this group. The primary endpoint was a statistically significant increase in adequate PPSV23 and influenza vaccination.MethodsIn 2017, rheumatology outpatients completed an anonymous questionnaire recording vaccination knowledge, status, and barriers. Simultaneously, a low-cost multifaceted quality improvement (QI) intervention was performed. All outpatients on oral...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
CONCLUSION: During the last century, AADRs among males declined more slowly than among females. Although the gap diminished in recent decades, exploration of social and behavioral factors may inform interventions that could further reduce death rates among males. PMID: 31804898 [PubMed - as supplied by publisher]
Source: Public Health Reports - Category: International Medicine & Public Health Tags: Public Health Rep Source Type: research
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