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Prostatectomy vs Radiotherapy: 15-Year Functional Outcomes Are the Same

Fifteen years after treatment for localized prostate cancer, men who underwent radical prostatectomy reported no differences in urinary, bowel, or sexual function compared with men who underwent external-beam...
Source: OncologySTAT Latest News - Category: Cancer & Oncology Source Type: news

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Publication date: Available online 14 April 2018 Source:Practical Radiation Oncology Author(s): Stephen A. Mihalcik, Jonathan J. Chipman, Martin G. Sanda, Meredith M. Regan, Irving D. Kaplan, Andrew A. Wagner, Catrina M. Crociani, Peter Chang
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 17 March 2018 Source:Hematology/Oncology Clinics of North America Author(s): Ron Shiloh, Monica KrishnanTeaser Several variables may be considered when deciding on optimal modality of radiation therapy for each cancer patient with bone pain, including prognosis, tumor histology, location and extent of metastases, and association with cord compression. Hypofractionated external beam radiation therapy is as effective as a multiple fraction radiotherapy course in most cases, although retreatment rates are higher after a single dose of radiation. Stereotactic body radiation may be used in ca...
Source: Hematology Oncology Clinics of North America - Category: Hematology Source Type: research
Abstract External beam radiotherapy (EBRT) is one of the curative treatment options for prostate cancer patients. The aim of this treatment option is to irradiate tumor tissue, while sparing normal tissue as much as possible. Frequent imaging during the course of the treatment (image guided radiotherapy) allows for determination of the location and shape of the prostate (target) and of the organs at risk. This information is used to increase accuracy in radiation dose delivery resulting in better tumor control and lower toxicity. Ultrasound imaging is harmless for the patient, it is cost-effective, and it allows f...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Combination therapy using external-beam radiotherapy (EBRT) with a brachytherapy boost has demonstrated superior biochemical control than dose-escalated EBRT alone. Whereas brachytherapy is disadvantageous bec...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
Standard treatment for patients with primary bone mPCa is systemic therapy with ADT. The HORRAD-trial was designed to evaluate the efficacy in patients randomized to either ADT or ADT plus external beam radiation therapy (EBRT) to the prostate. This is the first report presenting the primary outcome of this RCT, overall survival, on an intention-to-treat basis.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Advanced (including Drug  Therapy) I Source Type: research
Owing to increasing emphasis on value-based care, significant controversy has emerged surrounding both the diagnosis and subsequent treatment of prostate cancer (PCa), especially among men with limited life expectancy. We therefore sought to identify facility-level variation in the use of definitive therapy, defined as radical prostatectomy (RP), brachytherapy (BT) or external beam radiation (EBRT), among men diagnosed with clinically localized low-risk PCa and who are both older than 65 years of age and have a limited life expectancy (
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Epidemiology & Natural History II Source Type: research
Localized prostate cancer is effectively managed with any of several treatment modalities including prostatectomy, radiation (external-beam radiation therapy [EBRT], CyberKnife [CK], brachytherapy), and cryotherapy. Patients with prostate cancer refractory to primary treatment may undergo salvage treatment to control their cancer recurrence. One such salvage treatment is cryotherapy, controlled freezing of the prostate. We sought to determine how the choice of primary treatment affects the risk of biochemical recurrence (BCR) following salvage cryotherapy treatment for refractory prostate cancer.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Localized: Ablative Therapy II Source Type: research
A proportion of men who experience biochemical failure following external beam radiotherapy for prostate cancer remain with clinically localized disease. Salvage radical prostatectomy (sRP) and salvage cryotherapy (sCryo) are both treatment strategies that have been associated with durable recurrence free survival in such patients; however, there is a paucity of long-term comparative outcomes following these treatments. We compared long-term outcomes using mature data from two large single-center cohorts.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Prostate Cancer: Localized: Ablative Therapy II Source Type: research
External-beam radiation therapy (EBRT) plus androgen deprivation therapy (ADT) improves overall survival in men with localized and locally advanced prostate cancer (PCa). However, little is known about testosterone recovery after cessation of ADT combined with intensity-modulated radiation therapy (IMRT).
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Sexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy I Source Type: research
There are few reports in the literature on isolated bulbar urethral strictures after the treatment of prostate cancer because very often they merge indistinguishably with bladder neck contractures (BNC) after radical prostatectomy (RP) or with prostatic stenoses after irradiation (external beam or brachytherapy). We have reviewed our experience to identify such strictures, their clinical presentation and characteristics, their management and outcomes. Particular attention is paid to distinguishing post-surgical only from post-irradiation strictures.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Trauma/Reconstruction/Diversion: Urethral Reconstruction (including Stricture, Diverticulum) III Source Type: research
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