Prostatectomy vs Radiotherapy: 15-Year Functional Outcomes Are the Same

Fifteen years after treatment for localized prostate cancer, men who underwent radical prostatectomy reported no differences in urinary, bowel, or sexual function compared with men who underwent external-beam...
Source: OncologySTAT Latest News - Category: Cancer & Oncology Source Type: news

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DISCUSSION: This small, prospective case series suggests that, in the short term, HDR brachytherapy is safe and well tolerated in IBD patients. Therefore, IBD should not automatically disqualify patients from, at least, HDR brachytherapy. The reason why these results differ from previous LDR studies possibly reflects the benefit of inverse planning, which more readily achieves rectal dose constraints in HDR brachytherapy. PMID: 30099986 [PubMed - in process]
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Tags: Clin Oncol (R Coll Radiol) Source Type: research
AbstractPurposeRacial disparities are apparent in the management and outcomes for prostate cancer; however, disparities in compliance to quality measures for radiation therapy for prostate cancer have not been previously studied. Therefore, the goal of the study was to characterize disparities in the compliance rates with quality measures.MethodsThe comparative effectiveness analysis of radiation therapy and surgery study is a population-based, prospective cohort study that enrolled 3708 men with clinically localized prostate cancer from 2011 to 2012. Compliance with 5 radiation-specific quality measures endorsed by nation...
Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
Prostate cancer is the most common solid malignancy in men in the United States, affecting an estimated 240,000 men each year [1]. Fortunately, it is typically a slow-progressing cancer, and only approximately 14% of men with prostate cancer will die from the disease [2]. There is no clear evidence demonstrating improved survival from definitive treatment in patients with low-risk prostate cancer, which has led to controversy in how to best manage this group [2]. The National Comprehensive Cancer  Network treatment recommendations for low-risk prostate cancer with a life expectancy of 10 or more years include active s...
Source: Journal of the American College of Radiology : JACR - Category: Radiology Authors: Tags: Case studies in clinical practice management Source Type: research
In this study, we investigated the cost-effectiveness of these two modalities in the treatment of intermediate-high risk prostate cancer.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
Conclusions: Our study suggests HypoF EBRT can be delivered in combination with HDR for patients with ntermediate-risk and high-risk adenocarcinoma of the prostate without increasing toxicity compared to SF with an HDR boost. PMID: 30038640 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Authors: Chapman CH, Braunstein SE, Pouliot J, Noworolski SM, Weinberg V, Cunha A, Kurhanewicz J, Gottschalk AR, Roach MI, Hsu IC Abstract Purpose: Radiation dose escalation for prostate cancer improves biochemical control but is limited by toxicity. Magnetic resonance spectroscopic imaging (MRSI) can define dominant intraprostatic lesions (DIL). This phase I study evaluated dose escalation to MRSI-defined DIL using high-dose-rate (HDR) brachytherapy. Material and methods: Enrollment was closed early due to low accrual. Ten patients with prostate cancer (T2a-3b, Gleason 6-9, PSA
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
To the Editor Among 1809 men with prostate cancer and a Gleason score of 9 to 10, Dr Kishan and colleagues reported lower prostate cancer –specific mortality and longer time to distant metastases in men treated with external beam radiotherapy (EBRT) plus brachytherapy (BT) compared with radical prostatectomy or EBRT alone.
Source: JAMA - Category: General Medicine Source Type: research
In conclusion, a risk of urinary infections in cancer patients treated with pelvic radiotherapy was observed, in order to reduce the use of antibiotic resistance, preventive treatment with non-antibiotic agents 5 are warranted.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Conclusions The high agreement between treatment response, as assessed by 99mTc-MIP-1404 SPECT/CT and BR, suggests a possible role of that imaging tool for monitoring treatment in metastatic prostate cancer. Larger, ideally prospective trials are needed to help to reveal the full potential of SPECT imaging of PSMA expression in that regard.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research
Publication date: July 2018Source: European Urology, Volume 74, Issue 1Author(s): Mark Douglas Tyson, Tatsuki Koyama, Dan Lee, Karen E. Hoffman, Matthew J. Resnick, Xiao-Cheng Wu, Matthew R. Cooperberg, Michael Goodman, Sheldon Greenfield, Ann S. Hamilton, Mia Hashibe, Lisa E. Paddock, Antoinette Stroup, Vivien Chen, Ralph Conwill, Dan McCollum, David F. Penson, Daniel A. BarocasAbstractBackgroundWhether prostate cancer severity modifies patient-reported functional outcomes after radical prostatectomy (RP) or external beam radiotherapy (EBRT) for localized cancer is unknown.ObjectiveThe purpose of this study was to determi...
Source: European Urology - Category: Urology & Nephrology Source Type: research
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