Acetylcholinesterase-associated inflammation in patients with giant cell arteritis. Evaluation by histology and 11C-donepezil PET/CT.

CONCLUSIONS: AChE is highly expressed in the inflamed vessel wall of patients with GCA. Although, 11C-donepezil PET/CT showed no vascular uptake in the FDG PET/CT verified LV-GCA patients, histological findings raise the possibility that AChE can be used in the development of new diagnostic and disease monitoring tools for GCA. PMID: 31162030 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31162030?dopt=Abstract

Source: Clinical and Experimental Rheumatology - June 6, 2019 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research