Hepatitis A and E – differences and commonalities

Hepatitis A virus (HAV) and hepatitis E virus (HEV) are the most common causes of acute hepatitis in humans worldwide (1-7). The genomic structure of these viruses is shown in figure  1a and 1b. Both enterically transmitted hepatotropic viruses show a similar but not identical epidemiologic pattern, mode of transmission and clinical course (table 1). However, there are also some distinct genetic differences within the genome of the individual viruses with an impact on epidemio logy and transmission (Figure 1a and 1b) .

Source: Journal of Hepatology - June 3, 2019 Category: Gastroenterology Authors: Neta Gotlieb, Darius Moradpour, Daniel Shouval Tags: Hepatology Snapshot Source Type: research