Tu1987 THE RETROSPECTIVE COMPARISON BETWEEN SUBMUCOSAL TUNNELING ENDOSCOPIC RESECTION AND ENDOSCOPIC SUBMUCOSAL EXCAVATION FOR MANAGING ESOPHAGEAL SUBMUCOSAL TUMORS
Esophageal submucosal tumors (SMTs) are tissue protuberances covered with normal mucosa, usually without clinical symptoms. In esophagus, leiomyomas and gastrointestinal stromal tumors (GISTs) are two common SMTs and originate from the muscularis propria (MP) layer. The most are benign, but 10.8% leiomyomas might turn into leiomyosarcomas. GISTs are reported to be potentially malignant, especially with the large size or irregular boundary. Submucosal tunneling endoscopic resection (STER) and endoscopic submucosal excavation (ESE) are recently introduced to remove submucosal tumors (SMTs) originating from the muscularis propria (MP) layer.
Conclusions: Most cancers may be insensitive to social development. Internal factors, including aging, may be a key factor for the occurrence of cancer. PMID: 32462031 [PubMed - in process]
Uterine fibroids (leiomyoma) are benign monoclonal neoplasms of the myometrium and represent the most common tumors in women worldwide. Tumors occur in ∼77% of women overall and are clinically manifest in ∼25% by age 45 years. Although benign, these tumors are nonetheless associated with significant morbidity; they are the primary indication for hysterectomy, and a major source of gynecologic and reproductive dysfunction, ranging from profuse m enstrual bleeding and pelvic pain to infertility, recurrent miscarriage, and preterm labor.
Publication date: Available online 29 May 2020Source: International Journal of Surgery Case ReportsAuthor(s): Kaoru Wada, Hirofumi Tazawa, Toshiaki Komo, Naoto Hadano, Takashi Onoe, Takeshi Sudo, Yosuke Shimizu, Kazuya Kuraoka, Takahisa Suzuki, Hirotaka Tashiro
Publication date: Available online 29 May 2020Source: International Journal of Surgery Case ReportsAuthor(s): Erica Mazzotta, Sara Lauricella, Filippo Carannante, Gianluca Masciana, Marco Caricato, Gabriella T. Capolupo
In conclusion, although salvage surgery for structural recurrence of PTC has a high risk of complications, it may be worthwhile when macroscopic curative resection is available. The decision should be made considering various factors including curability, risk of surgical procedure, functional outcome, and life expectancy. PMID: 32461508 [PubMed - as supplied by publisher]
Publication date: Available online 29 May 2020Source: Annals of Medicine and SurgeryAuthor(s): Pushpa Veeralakshmanan, Ji Chung Tham, Amy Wright, Marilyn Bolter, Himanshu Wadhawan, Lee M. Humphreys, Grant Sanders, Tim Wheatley, Richard J. Berrisford, Arun Ariyarathenam
In this study, GSE20347, GSE23400 and GSE45670 datasets were retrieved from Gene Expression Omnibus (GEO) database, and the overlapping differentially expressed genes (DEGs) in three datasets were screened. Then the overlapping DEGs function was annotated by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway-enrichment analysis. The prognostic value of the top five KEGG pathway-related genes were further validated in The Cancer Genome Atlas (TCGA) database. After extensive statistical analysis, four genes (CDC25B, CXCL8, FZD6 and MCM4) were identified as potential prognostic markers. Among the four candidate genes, the...
CONCLUSIONS: People with schizophrenia do not have a higher overall incidence of cancer than people in the general population. However, there are significant differences in the risk of specific cancer types overall and by sex calling for efforts to develop disease-specific prevention programmes. In people with schizophrenia, higher risk generally occurs in those
Basavana Goudra, Preet Mohinder SinghSaudi Journal of Anaesthesia 2020 14(3):349-354 Providing sedation to patients undergoing gastrointestinal (GI) endoscopy is a controversial and emotive issue. The mainstay of sedation is propofol, whose administration is within the sole jurisdiction of anesthesia providers, at least in the USA. Attempts have been made to seize the authority by the GI community. One of the first attempts was the use of the prodrug of propofol –fospropofol. However, as the drug has a similar adverse effect profile as propofol in terms of respiratory depression, the FDA did not approve its use by p...
We present an interesting case of a preterm neonate with subglottic stenosis who was managed successfully with endoscopic release.