What do allergists in practice need to know about non –IgE-mediated food allergies

Unlike immunoglobulin (Ig) E –mediated food allergy (FA), in which 1 pathophysiological mechanism explains 1 disease process, non-IgE FA encapsulates a number of disease states caused by different mechanisms1,2 but unified in their ability to cause gastrointestinal inflammation. The commonest non–IgE-mediated disorders enco untered and managed by allergists include food protein–induced allergic proctocolitis (FPIAP), eosinophilic esophagitis (EoE), food protein–induced enteropathy (FPE), and food protein–induced enterocolitis syndrome (FPIES).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: MOC-CME Review Source Type: research