Berberine reverses LPS-induced repression of CYP7A1 through an anti-inflammatory effect

ConclusionBBR can offer an anti-inflammatory effect and reverse the inhibition of CYP7A1 and CYP8B1 expression caused by LPS treatment, as well as induce the production of bile acids in liver, probably via MAPK signaling; However, treatment with BBR had no effect on the size of total bile acid pool.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research