Ultrasensitive detection of lung cancer-associated miRNAs by multiple primer-mediated rolling circle amplification coupled with a graphene oxide fluorescence-based (MPRCA-GO) sensor

Analyst, 2019, Advance Article DOI: 10.1039/C9AN00517J, PaperKrissana Khoothiam, Kiatnida Treerattrakoon, Tawin Iempridee, Patraporn Luksirikul, Tararaj Dharakul, Deanpen Japrung MPRCA-GO sensor can detect low amount of miRNAs, which are biomarkers in cancer diagnosis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research

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Publication date: Available online 9 October 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): M. Brzeziński, B. Kost, S. Wedepohl, M. Socka, T. Biela, M. CalderónAbstractLung cancer is the leading cause of cancer death because of smoking and air pollution. Therefore, new ideas should be provided for lung cancer treatment in which the delivery of anticancer drugs to the local tumor site can be achieved. For this purpose, we propose the use of stereocomplexed spherical microspheres with sizes between 0.5 and 10 μm loaded with doxorubicin (DOX) to be administered through the nasal route. In order to gai...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
New J. Chem., 2019, Advance Article DOI: 10.1039/C9NJ04171K, PaperNirmalendu Biswas, Sachinath Bera, Nayim Sepay, Titas Kumar Mukhopadhyay, Krishnendu Acharya, Sandipta Ghosh, Swarnali Acharyya, Anup Kumar Biswas, Michael G. B. Drew, Tapas Ghosh Mixed-ligand complexes of VO2+ and VO3+ motifs incorporating a family of hydrazone ligands were reported, which exhibited promising cytotoxic activity against lung cancer cell line and antimicrobial activity against four pathogenic bacterial stains. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
CONCLUSION: Immune checkpoint inhibitors are a potential treatment for solid organ transplant patients despite the risk of graft rejection. PMID: 31611026 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
This case series demonstrates that cytoreductive surgery for diffused peritoneal metastases from lung cancer can yield improved prognosis and long-term survival.Journal of Medical Case Reports
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Canon Medical Systems USA has introduced Alphenix Aero Edition, a new interventional...Read more on AuntMinnie.comRelated Reading: Canon plans to open Middle East division Canon unveils Alphenix Encore Plus Program Canon's CT portfolio primed for lung cancer screening Canon installs 3T MRI scanner in Colo. Canon makes 1st Alphenix Core+ install in Fla.
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Authors: Russo A, de Miguel Perez D, Gunasekaran M, Scilla K, Lapidus R, Cooper B, Mehra R, Adamo V, Malapelle U, Rolfo C Abstract Introduction: The rise of the personalized era in lung cancer prompted the evaluation of novel diagnostic tools to overcome some of the limits of traditional tumor genotyping. Liquid biopsy refers to a multitude of minimally invasive techniques that can allow a real-time biomolecular characterization of the tumor through the analysis of human body fluids. Areas covered: Herein we provide a comprehensive overview of the role of liquid biopsy in lung cancer, mainly focusing on the most st...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Conclusion.Operable lung ADCs with EGFR TKI‐sensitizing mutations are associated with a high proportion of co‐mutations. Mutation profiling of these resected tumors could facilitate in determining the applicability and efficacy of adjuvant EGFR TKI therapeutic strategy.Implications for Practice.The efficacy of adjuvant epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) therapy for lung cancer harboring EGFR mutation after surgical resection is still under debate. Next‐generation sequencing of 416 cancer‐relevant genes in 139 resected lung cancers revealed the co‐mutational landscape with back...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Lung Cancer Source Type: research
ng Wenyi Kang Two novel water soluble heteroglycan (PCp-I and PCp-II) with anti-A549 lung cancer cells activity were isolated from Psoralea corylifolia L. Their average molecular weights were 2.721 × 104 and 2.850 × 104. PCp-I and PCp-II had the same monosaccharide composition, but their molar ratios were different. Based on methylation and NMR spectroscopy, the part structure of PCp-I was identified. The results of scanning electron microscope (SEM) showed that PCp-I had an irregular porous structure and PCp-II was flaky and irregularly curved. The results of thermogravimetry-differential scannin...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionMultiple patient-physician relationship factors account for variations in HRQOL and pain in cancer patients. These findings provide insight into potential targets for improving the patient-provider relationship and supportive cancer care outcomes.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
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