For Many With Mild Asthma, Popular Rx May Not Work: Study

Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Nursing, Pharmacy, Pulmonology, Asthma, Rheumatology, News, Source Type: news

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Authors: Lombardi C, Cottini M, Passalacqua G PMID: 30039694 [PubMed - indexed for MEDLINE]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Authors: Jeziorkowska R, Rożalski M, Skowroński K, Samochocki Z Abstract Introduction: Positive skin prick tests (SPT) results with protein allergens are the minor Hanifin and Rajka's atopic dermatitis (AD) criterion. In adults, they mainly concern aeroallergens. The inflammation of skin often prevents SPT, but does not exclude the assessment of serous specific immunoglobulin E (sIgE) concentrations. Aim: To assess usefulness of testing AD patients to aeroallergens with SPT and sIgE concentrations, and the correlation of these results and the clinical AD course. Material and methods: In 286 AD patients, t...
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Condition:   Asthma Interventions:   Drug: MCT;   Drug: Clazakizumab;   Drug: Broncho-Vaxom;   Drug: Imatinib Mesylate;   Drug: Cavosonstat;   Drug: Itacitinib;   Other: Placebo Sponsors:   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Pierce M, Hope HF, Kolade A, Gellatly J, Osam CS, Perchard R, Kosidou K, Dalman C, Morgan V, Di Prinzio P, Abel KM Abstract BACKGROUND: Children of parents with mental disorder face multiple challenges. AIMS: To summarise evidence about parental mental disorder and child physical health. METHOD: We searched seven databases for cohort or case-control studies quantifying associations between parental mental disorders (substance use, psychotic, mood, anxiety, obsessive-compulsive, post-traumatic stress and eating) and offspring physical health. Studies were excluded if: they reported perinatal outcomes only (
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Publication date: Available online 15 October 2019Source: Pharmacology &TherapeuticsAuthor(s): Edward D. Chan, Michael M. Chan, Mallory M. Chan, Paul E. MarikAbstractGlucocorticoids (GC) in all its various forms and formulations are likely one of the most commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic but are also associated with a myriad of acute and chronic side effects. It is fairly well-accepted in the medical community that GC can be life-saving when used in critically ill patients with severe exacerbations of asthma and chronic obstructive pulmonary disease, HIV-associated...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 15 October 2019Source: Journal of Herbal MedicineAuthor(s): Tarun Sharma, Snehasis JanaAbstractBoswellic acids (BAs) are the important active constituents of the plant Boswellia serrata which has been widely used for the treatment of several acute and chronic inflammatory diseases. These acids have shown their very potent anti-inflammatory activities in both in vitro and in vivo animal models. Also, their anti-arthritic, anti-rheumatic, anti-diarrhoeal, anti-hyperlipidemic, anti-asthmatic, anticancer, anti-microbial, analgesic activity, hepatoprotective, and immunomodulatory activities ha...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Circadian rhythms regulate and reflect many biological processes. Investigating circadian variability in biomarkers is important since the diurnal variability of any potential biomarker must be quantified and controlled in research and clinical practice. Time of day is particularly important in inflammatory diseases such as asthma, which are linked to exaggerated circadian rhythms. Airway narrowing in asthma is greatest at around 04:00 h and coincides with an increase in symptoms; asthma deaths are also more likely to occur at this time [1, 2]. Likewise eosinophilic airway inflammation peaks in the morning, with clini...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research
ng Yang Environmental air quality can affect asthma control and the development of overt asthmatic manifestations. In this population-based study, we investigated the effect of reinforcing a smoking ban in Taiwan through the enactment of the Tobacco Hazards and Prevention Act (THPA) on healthcare utilization rate by asthmatics. Analysis was performed based on data relevant to non-hospitalized asthmatic patients with insurance claims between 2005 and 2013 from the National Health Insurance Research Database of Taiwan, reported data on Asian dust storms, and penalty rates for violations of the tobacco ban. Poisson regres...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
AbstractThis systematic review aimed to synthesise multimorbidity profiling literature to identify replicable and clinically meaningful groupings of multimorbidity. We searched six electronic databases (Medline, EMBASE, PsycINFO, CINAHL, Scopus, and Web of Science) for articles reporting multimorbidity profiles. The identified profiles were synthesised with multidimensional scaling, stratified by type of statistical analysis used in the derivation of profiles. The 51 studies that met inclusion criteria reported results of 98 separate analyses of multimorbidity profiling, with a total of 407 multimorbidity profiles identifi...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
Condition:   Bronchial Asthma Intervention:   Sponsors:   Henan University of Traditional Chinese Medicine;   Henan Provincial Hospital;   Guangdong Provincial Hospital of Traditional Chinese Medicine Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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