Closing the door on social determinants of health and asthma disparities: Not so fast

Publication date: Available online 21 May 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elizabeth C. Matsui, Craig E. Pollack, Roger D. Peng, Corinne A. Keet
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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AbstractIn recent years, mold has been blamed for many symptoms or a constellation of symptoms. These symptoms are usually vague and subjective and difficult or impossible to measure or quantify. Moreover, there is no scientific evidence that mold has anything to do with these symptoms. In particular, the concept of toxic mold syndrome has permeated the public consciousness, and mycotoxins have falsely been associated with autoimmune diseases and a variety of other conditions. In fact, there is no evidence that the presence of mycotoxins in the air is enough to cause any disease known to man. Molds legitimately can cause a...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
SATURDAY, Oct. 12, 2019 -- Fall can be a challenging time of the year for kids with asthma, an expert says. " Although asthma can flare up for a number of reasons, a lot of people with allergies also have asthma, and asthma can be triggered by...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Contributor : Yujun YangSeries Type : Expression profiling by arrayOrganism : Mus musculusTIM-1 is a gene that regulates immune responses including transplantation tolerence, allergy and asthma, autoimmunity, viral infections as well as cancer, however its role in transplantation has not been evaluated. Here we use a murine model of graft versus host disease (GVHD) to evaluate the therapeutic potential of blocking TIM-1 using an antibody.We used microarray data to look for difference in gene expession in the gut which is one of the main organs that are afffected by GVHD as well as the spleen an organ when the immune respon...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
i Asthma is a chronic respiratory disease which is associated with higher levels of systemic inflammation. The causes of asthma remain poorly understood. Unhealthy diet and food allergy are potential risk factors for developing asthma. The prevalence of asthma in the Arabian Gulf region (AGR), and Kuwait, Saudi Arabia and Qatar in particular, is higher than in other Eastern Mediterranean countries. In the AGR, diets tend to be of low nutritional value due to high levels of total energy, cholesterol, sodium, added sugars and saturated fat, and low levels of fiber, fruit and vegetables. A few studies that include childre...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Commentary Source Type: research
In this study we observed an association between allergic disease and communication skills development as assessed by the Ages and Stages Questionnaire (ASQ) communication score, as a proxy for ASD, among children who participated in the Vitamin D Antenatal Asthma Reduction Trial (VDAART). In particular, we observed significant associations between both a diagnosis of eczema at age 3 years (OR=1.87; confidence interval [CI]: 0.97-3.47; p=0.054) and a diagnosis of food allergy at age 6 years (OR=3.61; 95% CI: 1.18-9.85; p=0.015) with ASQ communication score. Plasma metabolomics analyses suggest that dysregulated tryptophan ...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Among 6.1 million children with asthma,1 38% have uncontrolled asthma leading to increased pediatric emergency department (ED) visits, hospitalizations, and healthcare costs.2 Uncontrolled asthma unequally harms children from lower-income, racial and ethnic minority families.1 Disparities in asthma control have been attributed to differential exposures to poverty, living in unsafe, stressful neighborhoods, and unhealthy physical environments.3 One modifiable factor that may improve asthma control is the availability of neighborhood greenspace, i.e., land with grass, trees, or other vegetation.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Dr. Lipworth reports grants, personal fees and non-financial support from Astra Zeneca, grants, personal fees and non-financial support from Chiesi, other from GSK, during the conduct of the study; grants, personal fees and non-financial support from Boehringer Ingelheim, personal fees from Sanofi, personal fees from Teva, personal fees from Novartis, personal fees from Cipla, personal fees from Circassia, personal fees from Vectura, personal fees from Glenmark, personal fees from Dr Reddys, personal fees from Lupin, personal fees from Genentech, personal fees from Circassia, outside the submitted work.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Perspective Source Type: research
E. Johnston Residents of the Imperial Valley, a rural, agricultural border region in California, have raised concerns over high rates of pediatric asthma symptoms. There is an urgent need to understand the influences and predictors of children’s respiratory health in Imperial Valley. We assessed the impacts of sociodemographic, lifestyle, and household factors on children’s respiratory health and asthma prevalence by administering a survey to parents of elementary school children (n = 357) in northern Imperial Valley. We observed an overall asthma prevalence of 22.4% and respiratory symptoms and all...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
We describe a female diagnosed with non-allergic asthma. On March 24, 2016, examination of the skin-biopsy specimen revealed dense eosinophilic infiltration, and the Fip-1-like 1-platelet-derived growth factor receptor a fusion gene in peripheral blood mononuclear cells was negative. She was diagnosed with idiopathic hypereosinophilic syndrome. She was treated with intravenous methylprednisolone (MPSL), and subsequent oral MPSL. Then, she started to receive a monthly mepolizumab in June 2016, and successfully withdrew from daily use of oral MPSL. The patient has a mother diagnosed with non-allergic asthma. In February 2005...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
In conclusion this real-life study showed that during an ORL visit it is possible to suspect AR in children with turbinate hypertrophy, familial atopy, nasal pale mucosa, adenoid enlargement, and asthma comorbidity. PMID: 31594289 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
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