Preoperative Exposure to Benzodiazepines or Sedative/hypnotics Increases the Risk of Greater Filled Opioid Prescriptions After Surgery.

CONCLUSIONS: Patients exposed to benzodiazepines and sedative/hypnotics have prolonged use of opioids after surgery. Undergoing outpatient upper extremity surgery and being prescribed an opioid did not change the patterns of controlled substance use. Based on the results of this study, we are now more aware of the potential problems of patients with exposure to controlled substances, and are more attentive about reviewing their history of substance use in the PDMP website, an important resource. In addition, we now provide much more detailed preoperative counseling regarding the use and abuse of opioid medication in patients with exposure to benzodiazepines, sedatives, and those with a smoking history and mood disorders.Level of Evidence Level II, therapeutic study. PMID: 31094846 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31094846?dopt=Abstract

Source: Clinical Orthopaedics and Related Research - May 18, 2019 Category: Orthopaedics Authors: Hozack BA, Rivlin M, Lutsky KF, Graham J, Lucenti L, Foltz C, Beredjiklian PK Tags: Clin Orthop Relat Res Source Type: research