Modelling approach to obtain regional respiratory mechanics using electrical impedance tomography and volume-dependent elastance model
Objective: This paper presents a method for breath-by-breath estimation of regional respiratory
mechanics without the need for special manoeuvres (such as inspiratory pause or low-flow inflation)
using electrical impedance tomography (EIT) associated with pressure/airflow waveforms. Approach: We
developed a method to estimate regional parameters using the regional impedance fraction, by
multiplying it by global flow and volume waveforms. A volume-dependent elastance model was used to
obtain compliance, resistance, volume-independent ( E 1 ), and volume-dependent ( E 2 ) components.
Three swine under invasive mechanical ventilation were used to assess internal consistency and
illustrate potential applications of our method. One animal (case 1) was ventilated with a broad
range of tidal volumes to compare the consistency between regional and global resistances and
compliances. Two other animals (cases 2 and 3) had respiratory complian...
Source: Physiological Measurement - Category: Physiology Authors: M Victor, J Melo, R Rold án, M Nakamura, M Tucci, E Costa, M Amato, T Yoneyama and H Tanaka Source Type: research
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