Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice

Conclusions: Chronic psychosocial stress during adulthood is not sufficient to promote hemodynamic complications, organ dysfunction, metabolic disturbances and did not increase the risk of MOF after subsequent hemorrhage and resuscitation. Intravenous norepinephrine to keep target hemodynamics might have led to a certain level of oxidative stress in both groups and, therefore, disguised potential effects of chronic psychosocial stress on organ function after hemorrhagic shock in the present murine trauma model.
Source: Shock - Category: Emergency Medicine Tags: Basic Science Aspects Source Type: research