Dupilumab Improves Asthma Outcomes Irrespective of Frequency of Previous Asthma Exacerbation History.

Dupilumab Improves Asthma Outcomes Irrespective of Frequency of Previous Asthma Exacerbation History. Ann Allergy Asthma Immunol. 2019 May 07;: Authors: Corren J, Castro M, Ford LB, Bernstein JA, Jayawardena S, Maroni J, Rowe P, Amin N, Pirozzi G, Graham NMH, Khan A, Eckert L, Teper A PMID: 31075309 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research

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Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Erika J. Yoo, Nora L. Lee, Kelly P. Huang, Lara T. Kose, Deval Desai, Lauren A. Plante, Edward S. Schulman
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
ConclusionsThe effectiveness of LTRAs was not different from that of low-dose ICSs regarding the risk of asthma exacerbation in elderly patients with asthma in real-world settings. Given the practical benefits gained from convenient administration, LTRAs can be considered a reasonable alternative first-line therapy for elderly patients with mild asthma.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Čepelak I, Dodig S, Pavić I Abstract There is an increasing number of experimental, genetic and clinical evidence of atopic dermatitis expression as a pre-condition for later development of other atopic diseases such as asthma, food allergy and allergic rhinitis. Atopic dermatitis is a heterogeneous, recurrent childhood disease, also present in the adult age. It is increasingly attributed to systemic features and is characterized by immunological and skin barrier integrity and function dysregulation. To maintain the protective function of the skin barrier, in particular the maintenance of pH, hydration a...
Source: Biochemia Medica - Category: Biochemistry Tags: Biochem Med (Zagreb) Source Type: research
Consumption of certain foods during pregnancy has been shown to have beneficial effects on childhood asthma and allergic disease development and aggravation. However, most studies provide conflicting results a...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
Abstract Modern lifestyle with the increasing use of air conditioner (AC) has been linked with breathing difficulties, irritation, dryness, and other symptoms. Hence, dust mites were isolated from AC filters, which causes allergic diseases. A total of 95 dust samples were collected from AC filters from hospitals, guest house, office, school, and homes in Chandigarh, India. The highest concentration of dust mites was detected from hospitals (9/g), offices (7/g), households (6/g), guest houses (3/g), and schools (0/g). Based on the morphology of dust mites observed under a light microscope, Dermatophagoides and Acar...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a serious drug-induced delayed hypersensitivity reaction. DRESS can present various manifestations, and the major clinical manifestations are fever, skin rash, and the involvement of several internal organs.1, 2
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
An estimated 248 million individuals live with chronic hepatitis B infection worldwide [1]. Chronic hepatitis B infection (CH-B) has a high risk of progression to cirrhosis and hepatocellular carcinoma. Entecavir, a guanosine nucleoside analogue, is often the drug of choice in nucleoside-na ïve patients with CH-B because of its low rate of viral resistance. Resistance to entecavir therapy in nucleoside-naïve patients is approximately 1 percent after five years of treatment [2]. The efficacy and safety of entecavir has been well-studied in different patient populations with CH-B.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Coexistence of eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) has recently been increasingly recognized, however, literature in pediatrics, especially in-depth characterization of these patient characteristics is scarce (1-3). This case series aims to describe the characteristics of 6 children with coexisting EoE and IBD at a single tertiary care center.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Publication date: Available online 20 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Makoto Hoshino, Kenta Akitsu, Kengo KubotaAbstractBackgroundThe efficacy of the standardized quality (SQ) house dust mite (HDM) sublingual immunotherapy (SLIT) has been demonstrated for respiratory allergic disease. However, the effect of SLIT on inflammation and structural changes of the airways are still unknown.ObjectiveThe aim of this study was to assess the effects of the 6 SQ-HDM SLIT on airway inflammation and airway geometry in allergic asthma and rhinitis.MethodsOne hundred two asthmatic pat...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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