Decision Making in Indeterminate Thyroid Nodules and the Role of Molecular Testing

Cytologically indeterminate thyroid nodules are associated with a broad range (5% –75%) of malignant risk and accurately informing definitive management poses a challenge. Advancements in molecular testing of fine-needle aspiration biopsies have improved preoperative diagnostic accuracy and prognostication. For indeterminate nodules, such testing ideally will reduce the need fo r surgery for benign nodules and potentially guide appropriate extent of initial surgery for malignancy.
Source: Surgical Clinics of North America - Category: Surgery Authors: Source Type: research